Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1468 | Thyroid (non-cancer) | ECE2017

Ten years of TSH suppression therapy in differentiated thyroid cancer analysed by HR-pQCT

Germain Natacha , Nadin Katia , Estour Bruno , Galusca Bogdan

Introduction: TSH suppression therapy by thyroid hormones (TST) in patients with differentiated thyroid cancer (DTC) could be associated with adverse effects on bone metabolism in post-menopausal women. Recent recommendations suggest therefore to minimize time passed under TSH suppression therapy. However data in literature are controversial and few shows results on microarchitecture. This study evaluated bone microarchitecture using High-resolution peripheral quantitative com...

ea0049oc11.5 | Obesity | ECE2017

Differentiating constitutional thinness from anorexia nervosa in DSM 5 era

Estour Bruno , Marouani Nesrine , Sigaud Torrance , Lang Francois , Fakra Eric , Diamonde Aurelie , Galusca Bogdan , Germain Natacha

Introduction: Constitutional thinness (CT) is an underweight state characterized by normal menstruations and no change in feeding behaviour. Thinness is the only resemblance between Anorexia Nervosa (AN) and CT. Removal of amenorrhea in the new DSM 5 definition of AN might lead to misdiagnosis between these two populations. The objective of this study was to compare CT, AN and Control subjects in terms of biological, anthropometric, and psychological markers in order to better...

ea0049ep1126 | Female Reproduction | ECE2017

Graduated response to pulsatile GnRH therapy in hypothalamic amenorrhea

Germain Natacha , Fauconnier Anais , Klein Jean-Philippe , Wargny Amelie , Khalfallah Yadh , Papastathi-Boureau Chrysoula , Estour Bruno , Galusca Bogdan

Introduction: Pulsatile GnRH therapy is currently used to restore LH pulse and induce physiological ovulation, with effectiveness demonstrated in all types of hypothalamic amenorrhea (HA). Anorexia nervosa (AN) is characterized by self-starvation-induced undernutrition leading to functional hypothalamic amenorrhea (HA). Weight recovery does not always restore menses despite no apparent clinical and biological undernutrition residual signs. Only few specific studies on persiste...